pentobarbital will reduce the level or influence of lopinavir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.pentobarbital decreases amounts of panobinostat by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Potent CYP3A4 inducers can cut down panobinostat levels by ~70% and result in remedy fa